Using Immunopeptidomics to Identify Auto-antigens: Neutrophil Extracellular Traps

Time: 3:30 pm
day: Day One


• Neutrophil extracellular traps (NETs) are a powerful tool that neutrophils use to capture and eliminate pathogens but are also associated with autoimmune conditions like lupus and rheumatoid arthritis.
• Post-translational modifications of self-proteins associated with NETs could stimulate non-self immune responses to drive autoimmune activation.
• Identification of NET-associated antigens presented by antigen-presenting cells may help to better understand the etiology of these diseases.